The site in Glasgow has been open since July last year
The NHS Louisa Jordan is set to close tomorrow, with the vaccination centre being moved to the Hydro next week.
Since July 2020, the hospital has played a critical role in the fight against Covid-19.
The hospital has carried out more than 32,000 healthcare appointments, training over 6,900 healthcare staff and students and vaccinating about 175,000 people.
Today will be the last day of outpatient and diagnostic appointments, all training and blood donations.
Vaccinations will continue until Saturday at the current site, and move to the Hydro location within the Scottish Events Campus from Tuesday.
Once relocated to the SSE Hydro, the NHS Louisa Jordan vaccination centre will continue, in partnership with other NHS Boards, to run daily clinics for members of the public to receive their Covid-19 vaccination with the ability to administer up to 10,000 vaccinations per day.